Fig. 4

Species comparison of Mrc1 mRNA and CD206 protein. Treatments and data presentation are as in Fig. 1. a Mrc1 mRNA expression (mRNA counts/200 ng total RNA) was determined by NanoString analysis (mean ± SEM; n = 4–6 individual cultures), and plotted on the same Y-axis scale. b Representative Western blots of CD206 protein. c Summary of fold changes in CD206 protein expression (mean ± SEM; n = 4–6 individual cultures for mouse and 22 for rat), normalized to the total protein in each lane, and then to control microglia as in Fig. 1. Significant differences from unstimulated (control) cells are indicated: *p < 0.5; **p < 0.01; ***p < 0.001; ****p < 0.0001