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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Neuroinflammation contributes to autophagy flux blockage in the neurons of rostral ventrolateral medulla in stress-induced hypertension rats

Fig. 1

Representative gels (inset) or densitometric analysis (a) of protein level of ionized calcium-binding adaptor molecule-1 (Iba-1) detected from RVLM of SIH rats or age-matched normotensive rats or IC infusion of minocycline for 1 week in SIH rats. Microglial activation expressed as a percent of total microglia (b) in RVLM or adjacent to it and total number of microglia (activated + non-activated) in the same region. Photomicrographs showed microglia (c) taken from the RVLM of rats in different groups. The outline of the RVLM is highlighted by the dashed lines. Values are mean ± SEM of quadruplicate analyses on samples pooled from five to eight animals in each group. *P < 0.05 vs. control rats, and #P < 0.05 vs. the SIH group in the post hoc Scheffé multiple range analysis. RVLM rostral ventrolateral medulla. Bar = 50 μm in the top and 200 μm at the bottom panel of c

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