Fig. 2
From: Safety and in vivo immune assessment of escalating doses of oral laquinimod in patients with RRMS
Dose-dependent effect of laquinimod (LAQ) on the frequency of monocytes and slanDC. Sample sizes for slanDC (%) relative change from baseline: placebo n = 20, 0.9 mg LAQ n = 4, 1.2 mg LAQ n = 6, 1.5 mg LAQ n = 9, 1.8 mg LAQ n = 7, 2.1 mg LAQ n = 9, 2.4 mg LAQ n = 8, 2.7 mg LAQ n = 6. Sample sizes for monocyte (%) relative change from baseline: placebo n = 20, 0.9 mg LAQ n = 4, 1.2 mg LAQ n = 6, 1.5 mg LAQ n = 9, 1.8 mg LAQ n = 9, 2.1 mg LAQ n = 10, 2.4 mg LAQ n = 10, 2.7 mg LAQ n = 8. BL baseline, fm from, LAQ laquinimod, Rel. relative, slanDC 6-sulpho LacNAc+ dendritic cell