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Table 4 Modulating effects of laquinimod on activation status of slanDC

From: Safety and in vivo immune assessment of escalating doses of oral laquinimod in patients with RRMS

  Placebo Laquinimod
Parameter n Mean Std Err n Mean Std Err
SlanDC CD83-culture LPS (%) difference from baseline 13 −2.3 5.6 31 −18.8 4.2
SlanDC CD83-culture R848 (%) difference from baseline 13 −5.5 6.4 31 −16.5 3.2
SlanDC TNF-culture LPS (%) difference from baseline 15 −3.0 3.2 37 −9.4 2.5
SlanDC TNF-culture R848 (%) difference from baseline 15 −2.3 3.1 37 −8.9 2.3
  1. LPS lipopolysaccharide, slanDC 6-sulpho LacNAc + dendritic cell, Std Err standard error, TNF tumor necrosis factor