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Table 4 Modulating effects of laquinimod on activation status of slanDC

From: Safety and in vivo immune assessment of escalating doses of oral laquinimod in patients with RRMS

 

Placebo

Laquinimod

Parameter

n

Mean

Std Err

n

Mean

Std Err

SlanDC CD83-culture LPS (%) difference from baseline

13

−2.3

5.6

31

−18.8

4.2

SlanDC CD83-culture R848 (%) difference from baseline

13

−5.5

6.4

31

−16.5

3.2

SlanDC TNF-culture LPS (%) difference from baseline

15

−3.0

3.2

37

−9.4

2.5

SlanDC TNF-culture R848 (%) difference from baseline

15

−2.3

3.1

37

−8.9

2.3

  1. LPS lipopolysaccharide, slanDC 6-sulpho LacNAc + dendritic cell, Std Err standard error, TNF tumor necrosis factor