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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Brain ureido degenerative protein modifications are associated with neuroinflammation and proteinopathy in Alzheimer’s disease with cerebrovascular disease

Fig. 1

Profiling of the soluble and particulate brain proteomes in AD + CVD. a Grand mean ion intensity of the most abundant peptides from the AD + CVD and age-matched control particulate proteomes. b Enrichment analysis of the dementia-specific proteins identified in the particulate proteomes of AD + CVD. c Distribution of citrulline sites in the soluble and particulate proteomes of AD + CVD and age-matched controls. d Distribution of citrulline non-modified counterpart peptides in the soluble and particulate proteomes of AD + CVD and age-matched controls. e Distribution of homocitrulline sites in the soluble and particulate proteomes of AD + CVD and age-matched controls. f Distribution of homocitrulline non-modified counterpart peptides in the soluble and particulate proteomes of AD + CVD and age-matched controls. Data is reported as mean + SD (*p < 0.05 one-tailed Student’s t test. **p < 0.05 two-tailed Student’s t test)

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Journal of Neuroinflammation

ISSN: 1742-2094