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Table 2 CXCL13 concentrations in different disease groups

From: Cerebrospinal fluid CXCL13 as a diagnostic marker of neuroborreliosis in children: a retrospective case-control study

  AI Pleo. n CXCL13a (pg/ml) CXCL13>COb
Definite LNB + + 53 774.7 (4.5–13487) 52 (98)
Possible LNB    41 16.7 (4.5–1418.6) 11 (27)
 AI neg. + 27 25.0 (4.5–384.1) 9 (33)
 AI nd. nd + 13 8.1 (4.5–1418.6) 2 (15)
 AI pos. + 1 13.9 0 (0)
Non-LNB    91 4.5 (4.5–816.1) 3 (3)
 VZV −/+ 4 78.4 (4.5–239.9) 2 (50)
 Enterovirus −/+ 20 5.8 (4.5–816.1) 1 (5)
 TBEV + 5 8.7 (6.7–19.9) 0 (0)
 Inflammatory 8 4.5 (4.5–21.1) 0 (0)
 Facial palsy 19 4.5 (4.5–14.6) 0 (0)
 Headache 11 4.5 (4.5–7.4) 0 (0)
 Others 24 4.5 (4.5–50.4) 0 (0)
Total    185 10.4 (4.5–13487) 66 (36)
  1. The “Inflammatory” group included three Guillain-Barré syndrome, three retrobulbar optic neuritis, one acute disseminated encephalomyelitis (ADEM), and one parainfectious brainstem encephalitis
  2. CO cut-off determined at 55 pg/ml in our study, LNB Lyme neuroborreliosis, AI antibody index, Pleo. pleocytosis (>5 cells/ul in CSF), n numbers, neg. negative, nd not determined, pos. positive, VZV varicella-zoster virus, TBEV tick-borne encephalitis virus
  3. aData are presented as median (range)
  4. bData are presented as number (%)