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Table 2 CXCL13 concentrations in different disease groups

From: Cerebrospinal fluid CXCL13 as a diagnostic marker of neuroborreliosis in children: a retrospective case-control study

 

AI

Pleo.

n

CXCL13a (pg/ml)

CXCL13>COb

Definite LNB

+

+

53

774.7 (4.5–13487)

52 (98)

Possible LNB

  

41

16.7 (4.5–1418.6)

11 (27)

 AI neg.

+

27

25.0 (4.5–384.1)

9 (33)

 AI nd.

nd

+

13

8.1 (4.5–1418.6)

2 (15)

 AI pos.

+

1

13.9

0 (0)

Non-LNB

  

91

4.5 (4.5–816.1)

3 (3)

 VZV

−/+

4

78.4 (4.5–239.9)

2 (50)

 Enterovirus

−/+

20

5.8 (4.5–816.1)

1 (5)

 TBEV

+

5

8.7 (6.7–19.9)

0 (0)

 Inflammatory

8

4.5 (4.5–21.1)

0 (0)

 Facial palsy

19

4.5 (4.5–14.6)

0 (0)

 Headache

11

4.5 (4.5–7.4)

0 (0)

 Others

24

4.5 (4.5–50.4)

0 (0)

Total

  

185

10.4 (4.5–13487)

66 (36)

  1. The “Inflammatory” group included three Guillain-Barré syndrome, three retrobulbar optic neuritis, one acute disseminated encephalomyelitis (ADEM), and one parainfectious brainstem encephalitis
  2. CO cut-off determined at 55 pg/ml in our study, LNB Lyme neuroborreliosis, AI antibody index, Pleo. pleocytosis (>5 cells/ul in CSF), n numbers, neg. negative, nd not determined, pos. positive, VZV varicella-zoster virus, TBEV tick-borne encephalitis virus
  3. aData are presented as median (range)
  4. bData are presented as number (%)