Fig. 2

Hypothalamic transcripts differentially expressed between obesity-prone and obesity-resistant mice. a The cDNA obtained from hypothalamic RNA was employed in a real-time PCR array to determine the relative transcript expression in mice fed chow or obesity-prone (OP) and obesity-resistant (OR) mice fed on a high-fat diet (HFD) for 1 day; only the transcripts undergoing significant difference from control are presented; the results are presented as transcript expression relative to chow; the identity of the transcripts is presented in Additional file 1: Table S2. b The relative expression of LIF transcript was determined by real-time PCR in hypothalamic samples from control (CTL) mice, fed on chow, or OP and OR mice fed on HFD for 1 day. In a n = 3; in b n = 5; p = 0.06 vs. OP