Fig. 6
From: Inhibition of hypothalamic leukemia inhibitory factor exacerbates diet-induced obesity phenotype
Respirometry and spontaneous activity in mice treated with anti-LIF antibody. Mice were treated according to the protocol presented in Fig. 3a and parameters were determined at the end of the experimental period. In respirometry, vO2 (a, b) and vCO2 (c, d) were measured during a 24-h period (a, c) and the means during light and dark periods were calculated (b, d). The respiratory quotient (RQ) was calculated during the 24-h period (e) and means were obtained during the light and dark periods (f). Spontaneous activity was determined during a 24-h period (g). In all experiments n = 5; *p < 0.05. OP IgG, obesity-prone mice treated with non-immune IgG; OR IgG, obesity-resistant mice treated with non-immune IgG; OR anti-LIF, obesity-resistant mice treated with anti-LIF antibody