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Table 1 Cohort demographics

From: Using blood cytokine measures to define high inflammatory biotype of schizophrenia and schizoaffective disorder

  Full cohort Cytokine groups
Demographic Control (n = 75) Schizophrenia (n = 90) Difference Con low (n = 46) Con elevated (n = 22) SCZ low (n = 43) SCZ elevated (n = 39) Difference
Age in years (median + range) 29 (20–50) 35 (20–51) U = 2339, p < 0.001 28 (20–50) 31 (22–49) 35 (20–51) 35 (20–50) H(3) = 13.41, p < 0.01
Gender 36 F:39 M 37 F:53 M χ2 = 0.787, p = 0.375 20 F:26 M 13 F:9 M 19 F:24 M 16F:23 M χ2 = 2.059, p = 0.560
RIN ± SD 7.89 ± 1.11 7.61 ± 1.00 U = 2666.5, p = 0.028 8.23 ± 0.60 7.79 ± 1.26 7.81 ± 0.67 7.42 ± 1.18 H(3) = 8.55, p = 0.036
Age of onset (in years and range)   22.7 (12–46)     22.5 (12–46) 22.8 (16–32) U = 920, p = 0.448
Duration of illness in years   13.0 ± 7.51     12.7 (3–29) 13.8 (2–31) U = 932.5, p = 0.382
PANSS positive   15.2 ± 4.56     15.0 ± 4.49 15.2 ± 4.43 t(80) = −0.187, p = 0.852
PANSS negative   14.4 ± 6.13     14.8 ± 5.70 13.7 ± 6.55 U = 714, p = 0.247
PANSS general   30.7 ± 8.80     30.3 ± 8.1 30.7 ± 9.3 U = 829, p = 0.930
PANSS total   60.3 ± 16.70     60.2 ± 15.4 59.6 ± 17.7 U = 796, p = 0.693
Mean daily chlorpromazine equivalent dose (mg)   558 ± 474     546 ± 489 569 ± 501 U = 834, p = 0.967
Body mass index   30.9 ± 6.46     30.4 ± 6.55 30.9 ± 6.41 t(69) = −0.341, p = 0.734
  1. Notes: All values, except age, are mean ± SD standard deviation, PANSS Positive and Negative Symptom Scale, RIN RNA integrity number