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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Homocysteine exaggerates microglia activation and neuroinflammation through microglia localized STAT3 overactivation following ischemic stroke

Fig. 3

The effect of Hcy on the expression of Iba1 and OX-42 in the contralateral nonischemic side. a, d Representative images of Iba1 (red) and OX-42 (red) staining in DG area of the hippocampus and the cerebral ischemic cortex. The blue staining represents DAPI. Overlays demonstrate the colocalization of Iba1 (or OX-42) and DAPI. Each right-hand column depicts a magnified image of the rectangular region of the corresponding image in the left column. Bar = 50 μm. b, c Quantification of Iba1-positive cells in the post-ischemic hippocampus and cerebral cortex. e, f Quantification of OX-42-positive cells in the post-ischemic hippocampus and cerebral cortex.The data are presented as the mean ± SD. Five rats in each group and 10 fields for each rat were examined. a p < 0.05 vs. the SHAM group, b p < 0.05 vs. the MCAO group

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