TY - JOUR AU - Quik, M. AU - Zhang, D. AU - McGregor, M. AU - Bordia, T. PY - 2015 DA - 2015// TI - Alpha7 nicotinic receptors as therapeutic targets for Parkinson’s disease JO - Biochem Pharmacol VL - 97 UR - https://doi.org/10.1016/j.bcp.2015.06.014 DO - 10.1016/j.bcp.2015.06.014 ID - Quik2015 ER - TY - JOUR AU - Bencherif, M. AU - Narla, S. T. AU - Stachowiak, M. S. PY - 2014 DA - 2014// TI - Alpha7 neuronal nicotinic receptor: a pluripotent target for diseases of the central nervous system JO - CNS Neurol Disord Drug Targets VL - 13 UR - https://doi.org/10.2174/1871527313666140711094525 DO - 10.2174/1871527313666140711094525 ID - Bencherif2014 ER - TY - JOUR AU - Kihara, T. AU - Sawada, H. AU - Nakamizo, T. AU - Kanki, R. AU - Yamashita, H. AU - Maelicke, A. AU - Shimohama, S. PY - 2004 DA - 2004// TI - Galantamine modulates nicotinic receptor and blocks Aβ-enhanced glutamate toxicity JO - Biochem Biophys Res Commun VL - 325 UR - https://doi.org/10.1016/j.bbrc.2004.10.132 DO - 10.1016/j.bbrc.2004.10.132 ID - Kihara2004 ER - TY - JOUR AU - Del Barrio, L. AU - Martin-de-Saavedra, M. D. AU - Romero, A. AU - Parada, E. AU - Egea, J. AU - Avila, J. AU - McIntosh, J. M. AU - Wonnacott, S. AU - Lopez, M. G. PY - 2011 DA - 2011// TI - Neurotoxicity induced by okadaic acid in the human neuroblastoma SH-SY5Y line can be differentially prevented by α7 and β2* nicotinic stimulation JO - Toxicol Sci VL - 123 UR - https://doi.org/10.1093/toxsci/kfr163 DO - 10.1093/toxsci/kfr163 ID - Del Barrio2011 ER - TY - JOUR AU - Parada, E. AU - Egea, J. AU - Romero, A. AU - del Barrio, L. AU - Garcia, A. G. AU - Lopez, M. G. PY - 2010 DA - 2010// TI - Poststress treatment with PNU282987 can rescue SH-SY5Y cells undergoing apoptosis via alpha7 nicotinic receptors linked to a Jak2/Akt/HO-1 signaling pathway JO - Free Radic Biol Med VL - 49 UR - https://doi.org/10.1016/j.freeradbiomed.2010.09.017 DO - 10.1016/j.freeradbiomed.2010.09.017 ID - Parada2010 ER - TY - JOUR AU - Li, Y. AU - King, M. A. AU - Meyer, E. M. PY - 2000 DA - 2000// TI - α7 nicotinic receptor-mediated protection against ethanol-induced oxidative stress and cytotoxicity in PC12 cells JO - Brain Res VL - 861 UR - https://doi.org/10.1016/S0006-8993(99)02457-9 DO - 10.1016/S0006-8993(99)02457-9 ID - Li2000 ER - TY - JOUR AU - Takada, Y. AU - Yonezawa, A. AU - Kume, T. AU - Katsuki, H. AU - Kaneko, S. AU - Sugimoto, H. AU - Akaike, A. PY - 2003 DA - 2003// TI - Nicotinic acetylcholine receptor-mediated neuroprotection by donepezil against glutamate neurotoxicity in rat cortical neurons JO - J Pharmacol Exp Ther VL - 306 UR - https://doi.org/10.1124/jpet.103.050104 DO - 10.1124/jpet.103.050104 ID - Takada2003 ER - TY - JOUR AU - Nakamizo, T. AU - Kawamata, J. AU - Yamashita, H. AU - Kanki, R. AU - Kihara, T. AU - Sawada, H. AU - Akaike, A. AU - Shimohama, S. PY - 2005 DA - 2005// TI - Stimulation of nicotinic acetylcholine receptors protects motor neurons JO - Biochem Biophys Res Commun VL - 330 UR - https://doi.org/10.1016/j.bbrc.2005.03.115 DO - 10.1016/j.bbrc.2005.03.115 ID - Nakamizo2005 ER - TY - JOUR AU - Jonnala, R. R. AU - Terry, A. V. AU - Buccafusco, J. J. PY - 2002 DA - 2002// TI - Nicotine increases the expression of high affinity nerve growth factor receptors in both in vitro and in vivo JO - Life Sci VL - 70 UR - https://doi.org/10.1016/S0024-3205(01)01529-6 DO - 10.1016/S0024-3205(01)01529-6 ID - Jonnala2002 ER - TY - JOUR AU - Egea, J. AU - Rosa, A. O. AU - Sobrado, M. AU - Gandia, L. AU - Lopez, M. G. AU - Garcia, A. G. PY - 2007 DA - 2007// TI - Neuroprotection afforded by nicotine against oxygen and glucose deprivation in hippocampal slices is lost in α7 nicotinic receptor knockout mice JO - Neuroscience VL - 145 UR - https://doi.org/10.1016/j.neuroscience.2006.12.036 DO - 10.1016/j.neuroscience.2006.12.036 ID - Egea2007 ER - TY - JOUR AU - Shen, J. -. x. AU - Yakel, J. L. PY - 2012 DA - 2012// TI - Functional α7 nicotinic ACh receptors on astrocytes in rat hippocampal CA1 slices JO - J Mol Neurosci VL - 48 UR - https://doi.org/10.1007/s12031-012-9719-3 DO - 10.1007/s12031-012-9719-3 ID - Shen2012 ER - TY - JOUR AU - Liu, Y. AU - Hu, J. AU - Wu, J. AU - Zhu, C. AU - Hui, Y. AU - Han, Y. AU - Huang, Z. AU - Ellsworth, K. AU - Fan, W. PY - 2012 DA - 2012// TI - α7 nicotinic acetylcholine receptor-mediated neuroprotection against dopaminergic neuron loss in an MPTP mouse model via inhibition of astrocyte activation JO - J Neuroinflammation VL - 9 ID - Liu2012 ER - TY - JOUR AU - Sugano, N. AU - Shimada, K. AU - Ito, K. AU - Murai, S. PY - 1998 DA - 1998// TI - Nicotine inhibits the production of inflammatory mediators in U937 cells through modulation of nuclear factor-kB activation JO - Biochem Biophys Res Commun VL - 252 UR - https://doi.org/10.1006/bbrc.1998.9599 DO - 10.1006/bbrc.1998.9599 ID - Sugano1998 ER - TY - JOUR AU - Wang, H. AU - Liao, H. AU - Ochani, M. AU - Justiniani, M. AU - Lin, X. AU - Yang, L. AU - Al-Abed, Y. AU - Wang, H. AU - Metz, C. AU - Miller, E. J. PY - 2004 DA - 2004// TI - Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis JO - Nat Med VL - 10 UR - https://doi.org/10.1038/nm1124 DO - 10.1038/nm1124 ID - Wang2004 ER - TY - JOUR AU - Han, Z. AU - Li, L. AU - Wang, L. AU - Degos, V. AU - Maze, M. AU - Su, H. PY - 2014 DA - 2014// TI - Alpha-7 nicotinic acetylcholine receptor agonist treatment reduces neuroinflammation, oxidative stress, and brain injury in mice with ischemic stroke and bone fracture JO - J Neurochem VL - 131 UR - https://doi.org/10.1111/jnc.12817 DO - 10.1111/jnc.12817 ID - Han2014 ER - TY - JOUR AU - Navarro, E. AU - Buendia, I. AU - Parada, E. AU - Leon, R. AU - Jansen-Duerr, P. AU - Pircher, H. AU - Egea, J. AU - Lopez, M. G. PY - 2015 DA - 2015// TI - Alpha7 nicotinic receptor activation protects against oxidative stress via heme-oxygenase I induction JO - Biochem Pharmacol VL - 97 UR - https://doi.org/10.1016/j.bcp.2015.07.022 DO - 10.1016/j.bcp.2015.07.022 ID - Navarro2015 ER - TY - JOUR AU - Osso, L. A. AU - Chan, J. R. PY - 2015 DA - 2015// TI - Astrocytes underlie neuroinflammatory memory impairment JO - Cell VL - 163 UR - https://doi.org/10.1016/j.cell.2015.12.001 DO - 10.1016/j.cell.2015.12.001 ID - Osso2015 ER - TY - JOUR AU - Habbas, S. AU - Santello, M. AU - Becker, D. AU - Stubbe, H. AU - Zappia, G. AU - Liaudet, N. AU - Klaus, F. R. AU - Kollias, G. AU - Fontana, A. AU - Pryce, C. R. PY - 2015 DA - 2015// TI - Neuroinflammatory TNFα impairs memory via astrocyte signaling JO - Cell VL - 163 UR - https://doi.org/10.1016/j.cell.2015.11.023 DO - 10.1016/j.cell.2015.11.023 ID - Habbas2015 ER - TY - JOUR AU - McCarthy, K. D. AU - de Vellis, J. PY - 1980 DA - 1980// TI - Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue JO - J Cell Biol VL - 85 UR - https://doi.org/10.1083/jcb.85.3.890 DO - 10.1083/jcb.85.3.890 ID - McCarthy1980 ER - TY - JOUR AU - Luo, W. AU - Friedman, M. S. AU - Shedden, K. AU - Hankenson, K. D. AU - Woolf, P. J. PY - 2009 DA - 2009// TI - GAGE: generally applicable gene set enrichment for pathway analysis JO - BMC Bioinformatics VL - 10 UR - https://doi.org/10.1186/1471-2105-10-161 DO - 10.1186/1471-2105-10-161 ID - Luo2009 ER - TY - JOUR AU - Carlsen, H. AU - Moskaug, J. Ø. AU - Fromm, S. H. AU - Blomhoff, R. PY - 2002 DA - 2002// TI - In vivo imaging of NF-κB activity JO - J Immunol VL - 168 UR - https://doi.org/10.4049/jimmunol.168.3.1441 DO - 10.4049/jimmunol.168.3.1441 ID - Carlsen2002 ER - TY - JOUR AU - Gorina, R. AU - Font-Nieves, M. AU - Márquez-Kisinousky, L. AU - Santalucia, T. AU - Planas, A. M. PY - 2011 DA - 2011// TI - Astrocyte TLR4 activation induces a proinflammatory environment through the interplay between MyD88-dependent NFκB signaling, MAPK, and Jak1/Stat1 pathways JO - Glia VL - 59 UR - https://doi.org/10.1002/glia.21094 DO - 10.1002/glia.21094 ID - Gorina2011 ER - TY - JOUR AU - Chen, Z. J. AU - Parent, L. AU - Maniatis, T. PY - 1996 DA - 1996// TI - Site-specific phosphorylation of IκBα by a novel ubiquitination-dependent protein kinase activity JO - Cell VL - 84 UR - https://doi.org/10.1016/S0092-8674(00)81064-8 DO - 10.1016/S0092-8674(00)81064-8 ID - Chen1996 ER - TY - JOUR AU - Alkalay, I. AU - Yaron, A. AU - Hatzubai, A. AU - Orian, A. AU - Ciechanover, A. AU - Ben-Neriah, Y. PY - 1995 DA - 1995// TI - Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway JO - Proc Natl Acad Sci VL - 92 UR - https://doi.org/10.1073/pnas.92.23.10599 DO - 10.1073/pnas.92.23.10599 ID - Alkalay1995 ER - TY - JOUR AU - Brennan, M. S. AU - Patel, H. AU - Allaire, N. AU - Thai, A. AU - Cullen, P. AU - Ryan, S. AU - Lukashev, M. AU - Bista, P. AU - Huang, R. AU - Rhodes, K. J. PY - 2016 DA - 2016// TI - Pharmacodynamics of dimethyl fumarate are tissue specific and involve NRF2-dependent and-independent mechanisms JO - Antioxid Redox Signal VL - 24 UR - https://doi.org/10.1089/ars.2015.6622 DO - 10.1089/ars.2015.6622 ID - Brennan2016 ER - TY - JOUR AU - Kem, W. R. AU - Mahnir, V. M. AU - Prokai, L. AU - Papke, R. L. AU - Cao, X. AU - LeFrancois, S. AU - Wildeboer, K. AU - Prokai-Tatrai, K. AU - Porter-Papke, J. AU - Soti, F. PY - 2004 DA - 2004// TI - Hydroxy metabolites of the Alzheimer’s drug candidate 3-[(2, 4-dimethoxy) benzylidene]-anabaseine dihydrochloride (GTS-21): their molecular properties, interactions with brain nicotinic receptors, and brain penetration JO - Mol Pharmacol VL - 65 UR - https://doi.org/10.1124/mol.65.1.56 DO - 10.1124/mol.65.1.56 ID - Kem2004 ER - TY - JOUR AU - Medeiros, R. AU - Castello, N. A. AU - Cheng, D. AU - Kitazawa, M. AU - Baglietto-Vargas, D. AU - Green, K. N. AU - Esbenshade, T. A. AU - Bitner, R. S. AU - Decker, M. W. AU - LaFerla, F. M. PY - 2014 DA - 2014// TI - α7 Nicotinic receptor agonist enhances cognition in aged 3xTg-AD mice with robust plaques and tangles JO - Am J Pathol VL - 184 UR - https://doi.org/10.1016/j.ajpath.2013.10.010 DO - 10.1016/j.ajpath.2013.10.010 ID - Medeiros2014 ER - TY - JOUR AU - Mazurov, A. A. AU - Kombo, D. C. AU - Hauser, T. A. AU - Miao, L. AU - Dull, G. AU - Genus, J. F. AU - Fedorov, N. B. AU - Benson, L. AU - Sidach, S. AU - Xiao, Y. PY - 2012 DA - 2012// TI - Discovery of (2S,3R)-N-[2-(pyridin-3-ylmethyl)-1-azabicyclo[2.2.2]oct-3-yl]benzo[b]furan-2-car boxamide (TC-5619), a selective alpha7 nicotinic acetylcholine receptor agonist, for the treatment of cognitive disorders JO - J Med Chem VL - 55 UR - https://doi.org/10.1021/jm301048a DO - 10.1021/jm301048a ID - Mazurov2012 ER - TY - JOUR AU - Liu, Y. AU - Zeng, X. AU - Hui, Y. AU - Zhu, C. AU - Wu, J. AU - Taylor, D. H. AU - Ji, J. AU - Fan, W. AU - Huang, Z. AU - Hu, J. PY - 2015 DA - 2015// TI - Activation of alpha7 nicotinic acetylcholine receptors protects astrocytes against oxidative stress-induced apoptosis: implications for Parkinson’s disease JO - Neuropharmacology VL - 91 UR - https://doi.org/10.1016/j.neuropharm.2014.11.028 DO - 10.1016/j.neuropharm.2014.11.028 ID - Liu2015 ER - TY - JOUR AU - Kim, J. E. AU - You, D. J. AU - Lee, C. AU - Ahn, C. AU - Seong, J. Y. AU - Hwang, J. I. PY - 2010 DA - 2010// TI - Suppression of NF-kappaB signaling by KEAP1 regulation of IKKbeta activity through autophagic degradation and inhibition of phosphorylation JO - Cell Signal VL - 22 UR - https://doi.org/10.1016/j.cellsig.2010.06.004 DO - 10.1016/j.cellsig.2010.06.004 ID - Kim2010 ER - TY - JOUR AU - Yu, M. AU - Li, H. AU - Liu, Q. AU - Liu, F. AU - Tang, L. AU - Li, C. AU - Yuan, Y. AU - Zhan, Y. AU - Xu, W. AU - Li, W. PY - 2011 DA - 2011// TI - Nuclear factor p65 interacts with Keap1 to repress the Nrf2-ARE pathway JO - Cell Signal VL - 23 UR - https://doi.org/10.1016/j.cellsig.2011.01.014 DO - 10.1016/j.cellsig.2011.01.014 ID - Yu2011 ER - TY - JOUR AU - Liu, G. H. AU - Qu, J. AU - Shen, X. PY - 2008 DA - 2008// TI - NF-kappaB/p65 antagonizes Nrf2-ARE pathway by depriving CBP from Nrf2 and facilitating recruitment of HDAC3 to MafK JO - Biochim Biophys Acta VL - 1783 UR - https://doi.org/10.1016/j.bbamcr.2008.01.002 DO - 10.1016/j.bbamcr.2008.01.002 ID - Liu2008 ER - TY - JOUR AU - Parada, E. AU - Egea, J. AU - Buendia, I. AU - Negredo, P. AU - Cunha, A. C. AU - Cardoso, S. AU - Soares, M. P. AU - Lopez, M. G. PY - 2013 DA - 2013// TI - The microglial α7-acetylcholine nicotinic receptor is a key element in promoting neuroprotection by inducing heme oxygenase-1 via nuclear factor erythroid-2-related factor 2 JO - Antioxid Redox Signal VL - 19 UR - https://doi.org/10.1089/ars.2012.4671 DO - 10.1089/ars.2012.4671 ID - Parada2013 ER - TY - JOUR AU - Sharma, G. AU - Vijayaraghavan, S. PY - 2001 DA - 2001// TI - Nicotinic cholinergic signaling in hippocampal astrocytes involves calcium-induced calcium release from intracellular stores JO - Proc Natl Acad Sci VL - 98 UR - https://doi.org/10.1073/pnas.071540198 DO - 10.1073/pnas.071540198 ID - Sharma2001 ER - TY - JOUR AU - Perea, G. AU - Araque, A. PY - 2005 DA - 2005// TI - Properties of synaptically evoked astrocyte calcium signal reveal synaptic information processing by astrocytes JO - J Neurosci VL - 25 UR - https://doi.org/10.1523/JNEUROSCI.3965-04.2005 DO - 10.1523/JNEUROSCI.3965-04.2005 ID - Perea2005 ER - TY - JOUR AU - Agulhon, C. AU - Petravicz, J. AU - McMullen, A. B. AU - Sweger, E. J. AU - Minton, S. K. AU - Taves, S. R. AU - Casper, K. B. AU - Fiacco, T. A. AU - McCarthy, K. D. PY - 2008 DA - 2008// TI - What is the role of astrocyte calcium in neurophysiology? JO - Neuron VL - 59 UR - https://doi.org/10.1016/j.neuron.2008.09.004 DO - 10.1016/j.neuron.2008.09.004 ID - Agulhon2008 ER - TY - JOUR AU - Poskanzer, K. E. AU - Yuste, R. PY - 2016 DA - 2016// TI - Astrocytes regulate cortical state switching in vivo JO - Proc Natl Acad Sci VL - 113 UR - https://doi.org/10.1073/pnas.1520759113 DO - 10.1073/pnas.1520759113 ID - Poskanzer2016 ER -