Skip to main content

Table 2 Comparisons of cytokine levels in four groups including FS, control, fever only with FS history, and afebrile seizure children

From: Analysis of plasma multiplex cytokines and increased level of IL-10 and IL-1Ra cytokines in febrile seizures

Cytokines

Febrile seizure (N = 50)

Control (N = 39)

Fever only with FS history (N = 12)

Afebrile seizure (N = 13)

p value

IFN-γ

29.8(4–220)

21.6(2.7–703)

21(5.0–266)

13.9(0.3–25.8)

0.047

IL-10

103.7(7.1–728)

34.0(1.4–832.4)

22.0(0.5–181)

5.0(0.3–65.3)

< 0.001

IL-1Ra

652(144–5667)

231(1.6–1461)

202(34–422)

200(0.3–3440)

< 0.001

IL-1β

2.8(2.8–16.2)

2.9(0.4–47.4)

2.2(0.4–25.4)

1.1(0.2–61.6)

0.300

IL-2

2.8(2.8–5.3)

2.8(0.3–17.1)

1.7(0.2–27.2)

0.9(0.1–42.2)

0.007

IL-6

16.9(1.3–798)

7.9(0.2–104.2)

6.5(0.2–71.4)

0.8(0.2–31.5)

0.001

IL-8

43.3(2.3–1711)

20.9(1.3–109.1)

35.5(2.6–589)

54.7(4.5–345.6)

0.030

  1. Data are presented as median (range), and the unit is pg/mL. Multiple comparison test (Bonferroni correction). A p value < 0.05 indicates a significant difference. Kruskal–Wallis test