Skip to main content
Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Elevated microRNA-129-5p level ameliorates neuroinflammation and blood-spinal cord barrier damage after ischemia-reperfusion by inhibiting HMGB1 and the TLR3-cytokine pathway

Fig. 6

Effects of the miR-129-5p mimic and mimic control on HMGB1 expression in specific cell types of the spinal cord after IR. a Representative photomicrographs showing the localization of the fluorescence signals for HMGB1 in neurons and microglia at 48 h after IR. Arrows indicate co-localization. Scale bars = 50 μm. b Quantification of HMGB1 signals was performed based on the average of three independent images. c Quantification of HMGB1-positive neurons and microglia in the spinal cords at 48 h after IR. Data are expressed as the mean ± SD. *P < 0.05 versus the Sham group. # P < 0.05 versus the IR group

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094