Fig. 4
From: Targeting the NLRP3 inflammasome to attenuate spinal cord injury in mice
BAY 11-7082 or A438079 attenuates microglia/macrophage activation and may regulate microglia/macrophage polarization 3 days after SCI. (a-d) Immunofluorescence labeling to estimate the number of CD68-positive cells(green fluorescence) 3 days after SCI. a:SCI;b:sham;c:SCI+ BAY11-7082; d:SCI+ A438079. (e) Quantification analysis of CD68-positive cells. (f) Quantification analysis of the ratio of Arg1/iNOS mRNA. HP (High power field, 225um×162um). *p < 0.05, **p < 0.01, ***p < 0.001, NS p > 0.05. Data are presented as the mean ± SEM, n=5. Scale bars are 25 μm