Fig. 1

Tibia destruction 14 days after Walker 256 cells inoculation. a Radiographs of the contralateral and ipsilateral tibia show the bone destruction in the tibia inoculated with cancer cells. b Histological images of tibia sections stained by hematoxylin-eosin. The arrows and asterisks indicate the bone destruction on trabecular surface and the cancer cells in bone marrow respectively