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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: The analgesic effects of triptolide in the bone cancer pain rats via inhibiting the upregulation of HDACs in spinal glial cells

Fig. 5

Effect of intrathecal T10 administration on astrocyte activation in the spinal dorsal horn (SDH) of BCP rats on POD 14. a Immunostaining of spinal sections showed the BCP-induced change of astrocyte marker, GFAP, in the SDH. b Quantitative analysis of the percentage of GFAP immunostaining surface in spinal cord laminae I–II and the whole SDH which showed the BCP-induced change (n = 4). c Immunostaining of GFAP in the ipsilateral SDH. d The percentage of GFAP immunostaining surface in the laminae I–II and whole SDH on the ipsilateral side. e Western blot analysis of the protein level of GFAP in the ipsilateral SDH, relative to sham + vehicle group (n = 5). Scale bar 100 μm. *p < 0.05 vs. sham + vehicle group; # p < 0.05 vs. BCP + vehicle group

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Journal of Neuroinflammation

ISSN: 1742-2094