Fig. 7

a Hippocampus and its magnification in CA1 and CA3 regions. Scale bar = 100 μm. b Neuroinflammation measured by astroglial (GFAP) and microglial (Iba1) activation ant its quantification. n = 7 to 8 in each group; *p < 0.05 and **p < 0.01 on post hoc analysis compared to S + S. c Neuronal cell death measured by cresyl violet and its quantification. n = 8 to 10 in each group; *p < 0.05, **p < 0.01, and ***p < 0.001 on post hoc analysis compared to S + S. d Amyloid-positive degenerative neurons measured by 4G8 and its quantification. n = 6 to 8 in each group, †p < 0.001 on post hoc analysis compared to other groups; MCAO middle cerebral artery occlusion, BCCAo bilateral common carotid artery occlusion, S + S sham + sham, S + B sham + BCCAo, M + S MCAO + sham, M + B MCAO + BCCAo