Skip to main content
Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Peripheral immune tolerance alleviates the intracranial lipopolysaccharide injection-induced neuroinflammation and protects the dopaminergic neurons from neuroinflammation-related neurotoxicity

Fig. 3

Repeated low-dose LPS intraperitoneal injection preconditioning did not cause inflammation in the SN. We investigated the levels of pro-inflammatory cytokines and the expression of Iba-1 in the right SN of rats at 1, 7, 14, and 28 days post to the peripheral LPS injection. There was no significant difference between the control group and any other time points of the LPS (i.p.) group in the amounts of TNF-α and IL-1β nor in the expression of Iba-1. a, b The levels of TNF-α (a) and IL-1β (b) in the right SN were detected by ELISA. c, d The expression of Iba-1 in the right SN was quantified by measuring band intensities using ImageJ software. The values were normalized to GAPDH. The data are presented as the mean ± SEM (n = 6)

Back to article page