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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Inhibiting the microglia activation improves the spatial memory and adult neurogenesis in rat hippocampus during 48 h of sleep deprivation

Fig. 2

Sleep deprivation induces changes in spatial memory, cytokine levels and glial cells immunoreactivity in rats. Behavioral study parameters. a Latency. b Path length. c Path efficiency. d Number of entries. e Time spent. Immunoreactivity of f GFAP. g Iba-1 in DG, CA1, and CA3 region of the hippocampus. Fold changes in the h pro-inflammatory cytokines. i Anti-inflammatory cytokines in the hippocampus. *p < 0.05 when compared to control treated with vehicle. Parametric and non-parametric Student t test was applied for the test parameters as required

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