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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Selective depletion of microglial progranulin in mice is not sufficient to cause neuronal ceroid lipofuscinosis or neuroinflammation

Fig. 5

Gene expression changes present in aged GrnKO mice are not recapitulated in Lyz-cKO mice. Evaluation of mRNA expression levels assessed by qRT-PCR of a CD68, b Lamp2, c Lamp1, d CD11b, e Iba1, and f GFAP in the thalamus of 18-month-old mice. N = 6 Ctrl, 8 Lyz-cKO, and 8 GrnKO mice. Data represent mean ± SEM. p values were calculated using Tukey’s multiple comparison test after one-way ANOVA

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