Table 1 Animal models of inflammatory neuropathies including references

 Lewis

Active

PNS myelin, P0(180–199), P2(53–78), P2(57–81)

Frequently used EAN models

rev. in [208] e.g., [209,210,211]

Active

PMP22

Mild course EAN

[78]

Active

PNS myelin + Cyclosporine A

CIDP-like chronic relapsing, not robust

[86]

Adoptive transfer

P0, P2, P0(180–199), P2(61–70), MAG

Rapid onset EAN, CIDP-like relapsing if transferred repeatedly

rev. in [94, 208]

 BN, SD, BUF, Wistar

Active

PNS myelin

Less-severe EAN course

[212]

 Dark Agouti

Active

PNS myelin

CIDP-like relapsing

[85]

 C57/B6

Active

P0(180–199), P0(106–125) + PTx

Varying effectiveness reported

[213, 214]

 IL10 over-expressing C57/B6

Spontaneous

–

CIDP-like, demyelination, muscle weakness, paralysis, axonal loss

[97]

 SJL

Active

P2

Mild course EAN

[215]

Myelin + PTx (+ IL-12)

Severe course EAN

[216]

 Balb/C

Adoptive transfer

Myelin basic protein

Peripheral and central demyelination

[217]

 NOD

Active

Oral C. jejuni

Mild course acute motor axonal neuropathy (AMAN)

[83]

 IL-10^−/− NOD

Active

Oral C. jejuni

Acute motor axonal neuropathy (AMAN)

[83]

 B7-2^−/− NOD

Spontaneous

–

Spontaneous autoimmune neuropathy

CIDP-like

[99]

Active

Oral C. jejuni

Acute inflammatory demyelinating polyneuropathy (AIDP)

[83]

 ICAM^−/− NOD

Spontaneous

–

Spontaneous autoimmune neuritis

[107]

 PD-1^−/− + H-2^b NOD

Spontaneous

Autoimmune peripheral neuropathy

[110]

 IL-2 mAb depleted NOD

Spontaneous

Autoimmune peripheral neuropathy

[106]

 Aire ^GW/+ NOD

Spontaneous

Autoimmune peripheral neuropathy, CIDP-like

[112]

 ICOS/ICOS-L^−/− NOD

Spontaneous

Multifocal autoimmune neuropathy

[111]

 Guinea pig

Active

PNS myelin

[218]

 Monkey

Active

PNS myelin, P2

[219]