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Table 7 Correlation between cytokine levels and ABC subscale 3 (stereotypy) score

From: MicroRNA expression changes in association with changes in interleukin-1ß/interleukin10 ratios produced by monocytes in autism spectrum disorders: their association with neuropsychiatric symptoms and comorbid conditions (observational study)

Stereotypy (ABC III)

 

IL-1ß/IL-10 ratio

Cytokines measured

Stimulants

High (N = 43)

Normal (N = 47)

Low (N = 18)

IL-1ß

None

0.0104a

− 0.1728

0.1151

 

LPS

0.1351

− 0.0961

− 0.1328

 

Zymosan

0.3671 (p < 0.05)

− 0.0671

0.146

 

CL097

0.5686 (p < 0.005)

− 0.0675

0.1416

 

ß-lactam

0.327

− 0.1262

− 0.3518

IL-6

None

0.0058

− 0.0023

− 0.0664

 

LPS

0.3605 (p < 0.05)

− 0.294

− 0.2102

 

Zymosan

0.3321

0.1932

− 0.2323

 

CL097

0.4092 (p < 0.02)

− 0.2431

0.0376

 

ß-lactam

0.4533 (p < 0.01)

0.0016

− 0.0066

TNF-α

None

0.0037

0.065

− 0.0944

 

LPS

0.2059

0.2085

− 0.0243

 

Zymosan

0.2343

0.2385

0.1416

 

CL097

0.2302

0.0841

− 0.312

 

ß-lactam

0.1778

0.1369

− 0.3429

IL-10

None

0.0849

0.0562

0.4867

 

LPS

− 0.1605

0.0094

0.5155 (p = 0.0592)

 

Zymosan

− 0.0049

0.2030

0.1018

 

CL097

0.2465

− 0.1753

− 0.0288

 

ß-lactam

− 0.0879

0.1662

0.0133

  1. aCorrelation coefficient by Spearman’s test between cytokine levels and scores of ABC subscale III (stereotypy). Stimulants used for cultures are shown in the column 2
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Journal of Neuroinflammation

ISSN: 1742-2094