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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Genetic deletion or pharmacological inhibition of soluble epoxide hydrolase reduces brain damage and attenuates neuroinflammation after intracerebral hemorrhage

Fig. 5

Pharmacological inhibition of sEH by AUDA reduced brain tissue damage and improved long-term neurological function after ICH. a Representative cresyl violet-stained images and quantitative data of lesion volumes at 1 and 28 days post-ICH. The scale bar is 2 mm. Effects of 10 μM AUDA on b mNSS, c rotarod performance, d beam walk traversing time, e hindlimb performance, f left-biased swings, and g body weight from 1 to 28 days post-ICH. Values are mean ± S.E.M.; *P < 0.05, **P < 0.01, and ***P < 0.001 vs. vehicle group (n = 5–6 mice/group for cresyl violet staining, Student’s t test; n = 13–14 mice/group for behavioral tests and body weight changes, repeated measures two-way ANOVA)

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