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Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: Pharmacologic activation of cholinergic alpha7 nicotinic receptors mitigates depressive-like behavior in a mouse model of chronic stress

Fig. 8

Chronic restraint stress (CRS)-induced microglial activation in mouse hippocampus is reversed by chronic DMXBA treatment. a Representative immunoblots and relative levels of Iba-1 protein in hippocampus. Results are shown as fold change relative to GAPDH protein level. b Iba-1 immunofluorescent staining and quantification analysis of positive cells in hippocampal sections. Scale bar, 30 μm. Con, control group. All data are expressed as mean ± SEM. n = 8 for protein expression; n = 4 for immunofluorescence assay. **P < 0.01 vs. control group; ## P < 0.01 vs. CRS 21d + Veh group

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