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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Contrasting effect of the latency-reversing agents bryostatin-1 and JQ1 on astrocyte-mediated neuroinflammation and brain neutrophil invasion

Fig. 3

Bryostatin-1 and JQ1 affect CCL2, IL-6, and IL-8 gene expression. Astrocytes were treated with JQ1, bryostatin-1, or JQ1 and bryostatin-1 for 4, 8, or 24 h. Next, total RNA was extracted to measure mRNA expression of a CCL2, b IL-6, and c IL-8 by RT-qPCR. Data from six different donors are presented in fold change over the untreated condition. Asterisks denote statistically significant data as defined by the non-parametric Friedman test followed by Dunn’s multiple comparison test (*P < 0.05 and **P < 0.01)

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