Fig. 4From: DNA repair protein APE1 is involved in host response during pneumococcal meningitis and its expression can be modulated by vitamin B6Effect of an additional dose of vitB6 on APE1 protein expression (a) and carbonyl content (b) in the CX/24 h. Western blot images reveal a reduction in the expression of different APE1 forms after vitB6 pre/post supplementation as indicated in the graph (a). Carbonyl content was significantly reduced after an extra dose of vitB6 (b). Each column from carbonyl data expresses the mean percentage (± SEM) relative to control CX/20 h (showed in Fig. 3c). Comparison between columns which show p < 0.05 were significant in Dunn’s post test. Groups: uninfected control animals (CTRL) (n = 3), infected animals (PM) without vitB6 treatment (n = 6), infected animals plus vitB6 treatment (PM/pre sup vitB6) (n = 9), and infected animals plus second dose of vitB6 treatment (PM/pre pos sup vitB6) (n = 5)Back to article page