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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Inhibition of cyclin-dependent kinase 5 affects early neuroinflammatory signalling in murine model of amyloid beta toxicity

Fig. 2

The effect of Aβ on astrocytes and glia activation in mouse hippocampus. Immunoreactivity of glial fibrillary acidic protein (GFAP) (a) and Iba1 (b) was analysed by SDS-PAGE and Western blotting in mouse hippocampus 3 h and 1, 3, 7, 14, 21 and 35 days after icv Aβ (0.5 nmol) injection. Representative pictures were shown. Results of densitometric analysis were normalised to immunoreactivity of GAPDH, as a loading control. Results are presented as the mean ± SEM from four independent experiments (n = 4) per time point. *p < 0.05; **p < 0.01; ***p < 0.001 versus control using a one-way ANOVA followed by the Bonferroni test. n.d. not detected

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Journal of Neuroinflammation

ISSN: 1742-2094