Fig. 4

After LPS-induced sepsis, different TCRs affect the development of white matter differently at PNDs 12, 26, and 60. a White matter volume of the corpus callosum at PND 12 after LPS injection in all three genotypes (WT: saline = 7 mice, LPS = 8 mice; Tcrd ^−/−: saline = 7 mice, LPS = 9 mice; Tcrα ^−/−: saline = 5 mice, LPS = 6 mice). b White matter volume at PND 26 after LPS injection in all three genotypes (WT: saline = 16 mice, LPS = 23 mice; Tcrd ^−/−: saline = 18 mice, LPS = 19 mice; Tcrα ^−/−: saline = 16 mice, LPS = 15 mice). c White matter volume at PND 60 after LPS injection in all three genotypes (WT: saline = 24 mice, LPS = 24 mice; Tcrd ^−/−: saline = 16 mice, LPS = 21 mice; Tcrα ^−/−: saline = 18 mice, LPS = 21 mice). Data are presented as means ± SD; two-way ANOVA with LSD for pairwise comparisons, *p < 0.05, **p < 0.01