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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Prenatal alcohol exposure is a risk factor for adult neuropathic pain via aberrant neuroimmune function

Fig. 5

PAE induced myeloid cells in the secondary lymphoid organs. Leukocytes displaying negative expression of B cell, T cell, and NK cell markers (P2 population in Fig. 4) were further analyzed for myeloid cell marker (CD11b/c) expression. a Bar graphs showing proportions of myeloid cells in the spleen, medial iliac lymph nodes, peritoneal cavity (PEC), and peripheral blood mononuclear cells (PBMN). Myeloid cell proportions were significantly increased in the spleen [t(5) = 4.49, **p=0.0065]  and in the lymph nodes [t(5) = 3.704, *p=0.0139] in PAE rats. b Representative flow cytometry plots of CD11b/c expression vs side scatter (SSC-A) in the spleen (top panels) and in the lymph node (bottom panels) from Sac and PAE rats is provided. Data are representative of two independent experiments. Sac (N = 3 rats) and PAE (N = 4 rats), in each experiment (total of Sac; N = 6 and PAE; N = 8). Asterisks indicate p < 0.05. The data are presented as the mean ± SEM

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