Fig. 2
From: Donepezil suppresses intracellular Ca2+ mobilization through the PI3K pathway in rodent microglia
Pretreatment with donepezil did not suppress the mRNA expression of both TNFR1 and TNFR2 in rodent microglial cells. a–c Bar graphs showing that pretreatment with 5 μM donepezil for 12 h did not affect the mRNA expression of both TNFR1 and TNFR2 in rat HAPI (a) and mouse primary (b, c) microglial cells we used. In addition, pretreatment with donepezil did not suppress the mRNA expression of both TNFR1 (b) and TNFR2 (c) stimulated by TNFα treatment (3 ng/mL) in mouse primary microglial cells. NS > 0.1 vs control. Note that the unit of TNFR1 is 10 to the minus 3rd power in a