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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Tenuigenin protects dopaminergic neurons from inflammation via suppressing NLRP3 inflammasome activation in microglia

Fig. 6

Tenuigenin attenuates microglia activation induced by LPS in SNc and suppress LPS-induced serum IL-1β production. a Immunostaining with Iba-1 to visualize the activation of microglia in the SNc of each group. Scale bar represents 200 μm (upper) or 50 μm (under). b Stereological counts of Iba-1-positive cells in the SNc of each group. c ELISA of IL-1β in serum of each group. n = 6 for each group. Data are expressed as mean ± SEM, one-way ANOVA, **p < 0.01 and ***p < 0.001 vs. saline group. # p < 0.05 and ## p < 0.01 vs. LPS group

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Journal of Neuroinflammation

ISSN: 1742-2094