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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Activation of dopamine D1 receptor decreased NLRP3-mediated inflammation in intracerebral hemorrhage mice

Fig. 7

DRD1 antagonist and IFN-beta siRNA reversed effects of A68930 on DRD1/IFN-beta/STAT1/NLRP3 signaling pathway after ICH. a Representative photographs of the expressions of proteins in DRD1/IFN-beta/STAT1/NLRP3 pathway in western blotting. b and c Bar graphs of quantitative analysis of DRD1, IFN-beta, IFN-beta receptor, p-STAT1, NLRP3, pro-caspase1, caspase1, pro-IL-1beta, and IL-1beta, respectively. *p < 0.05, **p < 0.01 versus sham; #p < 0.05, ##p < 0.01 versus vehicle; $p < 0.05, $$p < 0.01 versus A68930 group; &p < 0.05, &&p < 0.01 versus scramble siRNA group

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Journal of Neuroinflammation

ISSN: 1742-2094