Fig. 3

Magnetic resonance lesion volume measured in EAE mice brain. a T1-Gd-enhanced lesion volumes in four EAE mice measured at different time points after immunization. b T2 lesion volumes obtained in the same four EAE mice analyzed with T1-Gd MRI at different time points after immunization. Lesion volumes are expressed in millimeter cube and represented as single point including median; statistical analysis is performed using Mann-Whitney test