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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Transcriptional profile and Epstein-Barr virus infection status of laser-cut immune infiltrates from the brain of patients with progressive multiple sclerosis

Fig. 4

Differential expression of immune-related genes between lymphoid-like and diffuse immune infiltrates isolated from the MS brain meninges. Data obtained in 25 B cell follicle-like structures and 11 meningeal diffuse infiltrates were compared using the Mann–Whitney test; both statistically significant differences (p < 0.0125 to account for multiple comparisons) and trends (p ≥ 0.0125, < 0.05) are shown. Gene expression values are presented as 2−ΔCt relative to GAPDH. The lines inside the boxes represent the median value; boxes extend from the 25th to the 75th percentile, covering the interquartile range (IQR), and whiskers extend from 25th percentile − 1.5 IQR to the 75th percentile + 1.5 IQR. Maximum outliers outside the whiskers are represented by individual marks

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