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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: Porphyromonas gingivalis lipopolysaccharide induces cognitive dysfunction, mediated by neuronal inflammation via activation of the TLR4 signaling pathway in C57BL/6 mice

Fig. 9

Effects of P.gingivalis-LPS on mRNA and protein expression of inflammatory cytokines. RT-PCR and ELISA were performed to detect mRNA (a, c, e, g), and protein (b, d, f, h) levels of inflammatory cytokines. Administration of P.gingivalis-LPS induced high expression of inflammatory factors on genes and proteins, in comparison to the control group, whereas these changes were reversed by TAK-242. Data are presented as mean ± SEM; *p < 0.05, **p < 0.01,  and ***p < 0.001, compared to the control group; #p < 0.05, ##p < 0.01, and ###p < 0.001, compared to the P.gingivalis-LPS group

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Journal of Neuroinflammation

ISSN: 1742-2094