Fig. 1

Brain-specific miR-124 was downregulated in the LPS-stimulated BV2 cells. miR-124 expression level was determined using reverse transcription quantitative real-time PCR (RT-qPCR) and normalised with U6 RNA. a miR-124 expression in BV2 cells treated with different concentrations (0.1, 0.2, 0.5, and 1 μg/mL) of LPS for 24 h. b miR-124 expression in BV2 cells exposed to 1 μg/mL LPS for different durations (0, 1, 6, 12, and 24 h). The data are shown as the mean ± SE from three independent experiments. The fold change is statistically significant. The fold change is significant where *P < 0.05, **P < 0.01, and ***P < 0.001