Table 1 The metabolic parameters at baseline and after 12 weeks of either ND or HFD consumption

Body weight (g)

225 ± 2

459 ± 6*

540 ± 9*†

Food intake (g/day)

21 ± 0.5

21 ± 0.2

24 ± 0.2*†

Plasma glucose (mg/dl)

132.6 ± 6

137.7 ± 4

142.2 ± 5

Plasma insulin (ng/ml)

2.3 ± 0.3

4.6 ± 0.4*

6.0 ± 0.5*†

HOMA index

22.4 ± 5

41.7 ± 4*

63.4 ± 7*†

Plasma total cholesterol (mg/dl)

74.7 ± 2

72.5 ± 3

89.4 ± 3*†

Plasma total triglyceride (mg/dl)

61.1 ± 5

65.2 ± 3

66.1 ± 5

LDL cholesterol (mg/dl)

21.5 ± 3

21.9 ± 3

34.1 ± 3*†