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Table 1 The metabolic parameters at baseline and after 12 weeks of either ND or HFD consumption

From: Decreased microglial activation through gut-brain axis by prebiotics, probiotics, or synbiotics effectively restored cognitive function in obese-insulin resistant rats

Metabolic parameters Baseline ND HFD
Body weight (g) 225 ± 2 459 ± 6* 540 ± 9*†
Food intake (g/day) 21 ± 0.5 21 ± 0.2 24 ± 0.2*†
Plasma glucose (mg/dl) 132.6 ± 6 137.7 ± 4 142.2 ± 5
Plasma insulin (ng/ml) 2.3 ± 0.3 4.6 ± 0.4* 6.0 ± 0.5*†
HOMA index 22.4 ± 5 41.7 ± 4* 63.4 ± 7*†
Plasma total cholesterol (mg/dl) 74.7 ± 2 72.5 ± 3 89.4 ± 3*†
Plasma total triglyceride (mg/dl) 61.1 ± 5 65.2 ± 3 66.1 ± 5
LDL cholesterol (mg/dl) 21.5 ± 3 21.9 ± 3 34.1 ± 3*†
  1. *P < 0.05 in comparison with baseline group
  2. P < 0.05 in comparison with ND group