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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Evidence for the activation of pyroptotic and apoptotic pathways in RPE cells associated with NLRP3 inflammasome in the rodent eye

Fig. 7

Decline of XIAP gene expression levels in Aβ-stimulated eyes. a Reverse transcriptional PCR revealed a 90% reduction of XIAP mRNA in Aβ-stimulated eyes compared to controls. N ≥ 3, Student’s t test, *p < 0.05. b–c In whole retina protein lysates, there was a significant 33% decrease of the XIAP protein level in Aβ-stimulated eyes compared to reverse Aβ controls. Bands shown are technical triplicates of the same-pooled sample. N = 5, Mann-Whitney, *p < 0.05

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