Table 1 Summary of diagnostic evaluation
From: Systemic autoinflammation with intractable epilepsy managed with interleukin-1 blockade
Test | Results | Normal range |
|---|---|---|
White blood cell count (103/μL) | 13.1 | 4.5–13.0 |
Absolute neutrophil count (103/μL) | 10.2 | 1.8–8.0 |
Hemoglobin (g/dL) | 13.1 | 12.0–16.0 |
Platelet count (103/μL) | 300 | 135–466 |
AST (U/L) | 9 | 5–26 |
ALT (U/L) | 19 | 12–49 |
Albumin (g/dL) | 3.7 | 3.3–4.8 |
Total protein (g/dL) | 7.8 | 6.4–8.3 |
TSH (mcIU/mL) | 1.39 | 0.43–4.00 |
S100A8/A9 (ng/mL) | 5617 | 716–3004 |
S100A12 (ng/mL) | 429 | 32–385 |
Erythrocyte sedimentation rate (mm/h) | 30 | 0–20 |
C-reactive protein (mg/dL) | 2.8 | < 0.30 |
IgA (mg/dL) | 118 | 68–376 |
IgG (mg/dL) | 1050 | 724–1611 |
IgM (mg/dL) | 66 | 60–264 |
Anti-nuclear antibody | Negative | < 1:80 |
Extractable nuclear antigens (Jo-1, Ro, La, RNP, Sm) | Negative | |
Anti-dsDNA | Negative | |
Anti-phospholipid antibody panel | Negative | |
c-ANCA (U/mL) | 0 | 0–19 |
p-ANCA (U/mL) | 0 | 0–19 |
Anti-ASMA | Negative | |
Anti-LKM | Negative | |
Endomysial antibody | < 1:10 | < 1:10 |
Anti-thyroglobulin antibody (U/mL) | 10.1 | 10–114 |
Anti-thyroid peroxidase antibody (U/mL) | 6.6 | 5–33 |
Anti-ribosomal antibody (U/mL) | 0 | 0–40 |
Intrinsic factor blocking antibody | Negative | |
Anti-NMO antibody | Negative | |
Anti-NMDA receptor ab | Negative | |
Paraneoplastic panel | Negative | |
CSF RBC count (per mm3) | 29 | 0–4 |
CSF WBC count (per mm3) | 1 | 0–4 |
CSF protein (mg/dL) | 37 | 15–45 |
CSF glucose (mg/dL) | 43 | 40–70 |
CSF oligoclonal bands | 0 | 0–4 |
CSF index | 0.39 | 0.3–0.77 |