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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Unconjugated bilirubin induces pyroptosis in cultured rat cortical astrocytes

Fig. 2

Involvement of caspase-1 activation in the UCB-induced loss of cell viability. Cell viability was determined with modified indirect MTT assay and presented as a percentage of the control. a The cell viability after treatment with 50 μM UCB was decreased in a time-dependent manner. *p < 0.05, versus the control group (0 h); **p < 0.01, versus the control group (0 h); ***p < 0.001, versus the control group (0 h) using the chi-square test. b The cells in different groups were treated as previously described for 24 h. ***p < 0.001, versus the control group; #p < 0.05, versus the UCB group using the chi-square test. Four independent experiments were performed in duplicate

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