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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Secoisolariciresinol diglucoside is a blood-brain barrier protective and anti-inflammatory agent: implications for neuroinflammation

Fig. 5

SDG suppresses cytoskeletal re-arrangements in monocytes. FACS analysis of monocytes stimulated by 12 nM LDV peptide (VCAM/ICAM consensus sequence) [28] and treated with SDG (0 or 50 μM) for 4 h. Representative contour plots of FACS reads (a). b F/G actin ratio in monocytes treated with SDG. Ten thousand events were collected. Ratios of MFIs for F-actin and G-actin were calculated, and the levels of F/G actin in non-stimulated, non-treated cells were assigned a value of 1. Results are shown as the mean ± SD (**p < 0.05 vs. untreated control) from three independent experiments

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