Fig. 1From: The role of the complement system in traumatic brain injury: a reviewSchematic illustration of the complement cascade. The three activation pathways, the classical, alternative and lectin (MBL) pathways, are all included. Shown are the anaphylatoxins (C3a and C5a), which can trigger mast cell degranulation, and the MAC, which can lead to cell lysis. Adapted from Mathern and Heeger, 2015 [28]Back to article page