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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Lymphotoxin β receptor-mediated NFκB signaling promotes glial lineage differentiation and inhibits neuronal lineage differentiation in mouse brain neural stem/progenitor cells

Fig. 2

LTβR mRNA expression is enriched in mouse neural stem/progenitor cells. a Relative levels of LTβR mRNA expression in adult mouse SVZ NSCs/NPCs under proliferation or differentiation for 1 and 3 days. b Significant increase in LTβR mRNA levels during neural induction from embryonic stem cells (ESC), embryoid body (EB) to NSC. c Presence of LTβR mRNA expression in neurogenic tissues of adult mouse brain. In all the relative RT-qPCR analysis, representative amplification curve (log scale) for cycle threshold (Ct) values and melt peak curve for validation of pure PCR product are presented. Relative quantification of LTβR PCR product crossing exon 6–7 after β-actin or Ppia normalization. Data represent mean ± SEM of 3 experiments. **p < 0.01 indicate significant changes as compared to corresponding NSC (a) or ESC (b) group

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Journal of Neuroinflammation

ISSN: 1742-2094