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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Lymphotoxin β receptor-mediated NFκB signaling promotes glial lineage differentiation and inhibits neuronal lineage differentiation in mouse brain neural stem/progenitor cells

Fig. 4

Extensive expression of LTβR mRNA (a–d) and protein (e, f) in mouse brain, primarily on neurogenic zones (SGZ, SVZ), prefrontal cortex, hypothalamus and cerebellum. a–c In situ hybridization data of adult mouse brain sagittal section using LTβR antisense probe was collected from http://mouse.brain-map.org/gene/show/16770. Representative merged view of dentate gyrus and SVZ (c) showed strong expression of LTβR mRNA around the SGZ, granular layer and SVZ. d Relative expression levels of raw expression values (Log2:N). e, f Series coronal sections of adult mouse brain were immunostained for LTβR (green, 800 nm channel) and MBP (red, 700 nm channel) and scanned with Licor Odyssey CLX imager, showing expression pattern similar to in situ hybridization

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Journal of Neuroinflammation

ISSN: 1742-2094