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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Lymphotoxin β receptor-mediated NFκB signaling promotes glial lineage differentiation and inhibits neuronal lineage differentiation in mouse brain neural stem/progenitor cells

Fig. 5

Expression of LTβR-like immunoreactivity in subventricular zone (SVZ) and subgranular zone (SGZ) of adult mouse brain. Coronal brain sections underwent free-floating immunofluorescent immunohistochemistry with rabbit anti-LTβR antibody (red) together with goat anti-Calretinin (green) and mouse anti-NeuN (white) antibodies (a), chicken anti-Nestin (green) and goat anti-Sox2 (white) antibodies (b), chicken anti-GFAP (green) antibody (c), or goat anti-DCX (green) antibody (d) followed by corresponding Alexa Fluor® conjugated secondary antibodies and confocal image analysis. LTβR is primarily expressed in GFAP+/Sox2+ NSC (white arrow), some neuroblasts (red arrow) and mature neurons (yellow arrow). LV, lateral ventricle; DG, dentate gyrus

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