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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Upregulation of HMGB1-TLR4 inflammatory pathway in focal cortical dysplasia type II

Fig. 5

The expression and distribution of TLR4 and HMGB1 in oligodendrocytes of FCD lesion and control. Immunofluorescence double staining for the expression and oligodendrocytes localization of TLR4 and HMGB1. TLR4 immunoreactivity (in green) was not detected in oligodendrocytes which were visualized by the oligodendrocytic marker Olig2 (in red) in both of FCD and peri-FCD tissue (ah). HMGB1 was mainly colocalized with Hoechst 33342 in oligodendrocytes of both FCD and peri-FCD tissue (ip). Scale bars = 40 μm

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