Fig. 1From: The role of glucocorticoid, interleukin-1β, and antioxidants in prenatal stress effects on embryonic microgliaEffects of stress factors on total microglia and morphological subtype density in E14 cortical plate. Potential maternal stress factors included glucocorticoid stress hormone, corticosterone (Cort), and pro-inflammatory cytokine, IL-1β. a Microglia morphological subtypes (Iba1 in red and DAPI in blue). Scale bars 10 and 100 μm. b Corticosterone increased total and amoeboid microglia, but did not recapitulate the most significant effect of prenatal stress (solid line), increased multivacuolated microglia. c IL-1β increased total and amoeboid microglia. IL-1β increased multivacuolated microglia, but not to the extent of prenatal stress. (*p < 0.05 and **p < 0.01 compared to oil or saline). Previous findings on microglia density indicated by dotted line for non-stress (NS) and solid line for prenatal stress (PS) levels, [13].Back to article page