Fig. 4From: [18F]FSPG-PET reveals increased cystine/glutamate antiporter (xc-) activity in a mouse model of multiple sclerosisSignificant correlation between xCT protein levels in CNS tissues and in vivo PET signal. a Representative Western blot with actin and NaK-ATPase as loading controls (Ctrl). Correlation between xCT protein levels (determined by densitometric Western analysis) and [18F]FSPG uptake (determined by PET quantification) in the b cervical/thoracic spinal cord (SC), c lumbar SC, and d brain. ***p 0.0001–0.001, **p 0.001–0.01, *p 0.01–0.05Back to article page