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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Salidroside provides neuroprotection by modulating microglial polarization after cerebral ischemia

Fig. 2

SLDS induces changes in mRNA expression of M1 and M2 polarization markers after MCAO. RT-PCR was performed on mRNA isolated from ischemic brains 1, 3, 7, and 14 days after MCAO or sham operations. a SLDS decreased the mRNA expression of M1 polarization markers after MCAO. b SLDS increased the mRNA expression of M2 markers after MCAO. n = 4 to 5 per group. Data are expressed as mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001 vs. the corresponding days in the vehicle groups, by two-way ANOVA and Sidak’s multiple comparisons test

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