Fig. 3

Comparison of LOTUS concentrations in CSF between acute and recovery phases. a Representative immunoblots of CSF LOTUS in acute and recovery phase of three patients with meningitis. The concentration of LOTUS in the CSF was calculated using a standard curve generated from blot band intensities of recombinant protein. b LOTUS concentration in CSF of patients with viral (n = 18) and bacterial meningitis (n = 14). Horizontal dashed lines (192.1 ng/ml) represent mean LOTUS concentration in healthy controls. Values are means ± s.e.m. c Individual variation in CSF LOTUS concentration. Horizontal dashed lines (192.1 ng/ml) represent mean LOTUS concentration in healthy controls. P values were calculated by Wilcoxon matched-pairs signed-rank test